I created a profile for Jade Empire. To get it to work you have to load the game with the controller UNPLUGGED then plug it in. Do NOT run it as a persistent profile. This means loading from your normal desktop shortcut and not from the profiler window.
Also if you die, you will need to uplug the controller before clicking reload. Then plug the controller back in (after reloading) and it will work fine.
The d pad down button is set up as a cycle command for the different fight styles and the left analog stick is set up so that if you press it forward past a certain point the character will automatically run.